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Workshop: From DNA to Phenotype: Epigenetic Mechanisms in Resilience and Adaptatión
Robert Schneider. Professor at the Helmholtz Center Munich (Germany)
Gonzalo Millán. Junior Group Leader at CABIMER (Spain)
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pendiente inicio
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Desde: 15 Octubre 2024
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Hasta: 17 Octubre 2024
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Presencial
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Sede Antonio Machado de Baeza
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Investigadora
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Inglés
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20 horas
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400 euros
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35
Epigenetics at the forefront of Biomedical Research
The past three decades have witnessed major advances in our understanding of the molecular mechanisms behind epigenetic control of key cellular processes. Although most breakthroudiscoveries were driven by scientific curiosity, many of them have important implications for human health. This is based on the notion that, unlike genetic alterations, most of the known epigenetic modifications are likely reversible, which offers considerable promise for therapeutic intervention. Importantly, the writers, readers and erasers of epigenetic information are either enzymes or recognize small covalent modifications, thereby representing ideal drug targets. In fact, more than 10 drugs targeting epigenetic regulators have currently been approved for treating different diseases, and more than 60 other epigenetic drugs are in clinical trials. Although most of the epigenetic research is presently dedicated to cancer, the repurposing of epigenetic drugs for other diseases, including age-related diseases, is becoming common practice. Nowadays, over 80 companies have epigenetic drug development programs targeting different diseases. It is expected that these numbers will only grow through the years, making this research direction even more promising. Thus, we believe that the social significance of epigenetic studies makes this workshop proposal a relevant and timely opportunity to discuss new observations and discoveries in order to explore possible therapeutic opportunities.
Expected impact
This workshop proposal builds upon the scientific excellence of the invited speakers and the extensive experience of Prof. Robert Schneider in the successful organization of epigenetic-related scientific meetings (more than 16 different ones, both in Europe and the USA). Invited speakers were chosen on the basis of scientific merit within the context of each session topic. Important criteria included the novelty of the approach, the significance of the work, and impact of the findings to the society. We believe that this unique list of speakers investigating different aspect of Epigenetics and leveraging a variety of model organisms ensures a diverse range of perspectives and expertise that will undoubtedly enrich the workshop's impact and outcomes.
A major objective of this workshop proposal is to promote interaction between junior scientists (young PIs, postdoctoral fellows, graduate students) and well-recognized senior investigators in the field. In this regard, we strongly believe that both the venue and the small number of attendants provide a unique forum for fruitful discussions to exchange knowledge, share recent unpublished findings and foster collaborative efforts. Moreover, we have included a specific session in our proposal, Meet the Experts, an informal event designed to provide young scientists with an opportunity to meet leaders in the field to talk about science and network in smaller groups with an informal setting thereby encouraging discussion. We will suggest selected topics to start the conversation (i.e. emerging scientific questions in the field, mentorship and career choices in academia and industry), but want to encourage young investigators to use this opportunity to explore issues of their own interest.
Since we aim this workshop to make a deeper impact on the epigenetic community, we have also included another session in our proposal, The Power Hour, where relevant issues of interest for scientific researchers (i.e. women in science, work/family balance, scientific misconduct) will be discussed in round tables. The number of females invited speakers is 4 (~30% of the total), which probably reflects the overall gender composition of faculty level scientists working in the area of epigenetics. In an effort to further enhance the visibility of women in the field, the 4 females invited speakers will serve as session chairs, which will facilitate the identification and recruitment of junior women scientists for the selected talks.
To summarize, the two main goals of this workshop proposal are:
- Creating a forum to facilitate the presentation of unpublished, cutting-edge research by world-leader investigators from diverse aspects of Epigenetics, showcasing the latest advancements in the field.
Offering a valuable opportunity for young scientists engaged in epigenetics research to participate in insightful discussions on recent research developments in the field, fostering the initiation of collaborative endeavors.
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Plan de estudios
Preliminary program
Day 1 (15/10/24)
Opening talks9:00-9:15 Institutional welcome by UNIA
9:15-9:30 Opening of the Workshop by the organizers
Session 1. Epigenetic Mechanisms
Chair: Jessica Downs (The Institute of Cancer Research, United Kingdom)9:30-10:00 Adrian Bird – DNA methylation in mammals
10:00-10:30 Sylvia Erhardt – Epigenetic regulation of centromere identity
10:30-10:50 Selected talk
10:50-11:30 Coffee break
11:30-12:00 Robert Schneider – Epigenetic Regulation of cellular function
12:00-12:30 Gonzalo Millán – Novel histone PTMs in chromatin regulation
12:30-12:50 Selected talk
LUNCH (13:00-14:30)
Session 2. Developmental Epigenetics
Chair: Sylvia Erhardt (Karlsruhe Institute of Technology, Germany)14:30-15:00 Azim Surani – Epigenetic reprogramming in mammals
15:00-15:30 Pablo Navarro Gil – Epigenetic regulation during pluripotency
15:30-16:00 Daniel Martin Messerschmidt – Mammalian Developmental Epigenetics
16:00-16:20 Selected talk
16:20-17:00 Coffee break
17:00-17:30 Julie Ahringer –Epigenetics and 3D architecture in C.elegans
17:30-17:50 Selected talk
POSTER SESSION I AND REFRESHMENTS (18:00-19:30)
Day 2 (16/10/24)
Session 3. Transgenerational Epigenetics
Chair: Biola Javierre (Josep Carreras Leukaemia Research Institute, Spain)9:00-10:00 The Power Hour
10:00-10:30 Oliver J Rando – Soma to germline communication
10:30-10:50 Selected talk
11:00-11:30 Coffee break
11:30-12:00 Ueli Grossniklaus – Transgenerational Epigenetics in Plants
12:00-12:20 Selected talk
12:20-12:40 Selected talk
LUNCH (13:00-14:30)
14:30-15:00 Daniel Jarosz – Prion-based Epigenetics15:00-15:20 Selected talk
15:20-15:50 Hiten Madhani –Epigenetics in fungi
15:50-16:10 Selected talk
16:10-16:40 Coffee break
16:40-17:40 Meet the expert
POSTER SESSION II AND REFRESHMENTS (18:00-19:30)
Day 3 (17/10/24)
Session 4. Epigenetics in disease
Chair: Julie Ahringer (University of Cambridge, UK)9:00-9:30 Jessica Downs – Epigenetics and Genome Instability
9:30-10:00 Biola Javierre – 3D genome organization in health and Disease
10:00-10:20 Selected talk
10:20-10:50 Wolf Reik– Epigenetic reprogramming in ageing
10:50-11:00 Closing Remarks & Meeting Wrap up
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Robert Schneider. Professor at the Helmholtz Center Munich (Germany)
Gonzalo Millán. Junior Group Leader at CABIMER (Spain)
Adrian Bird, Professor at the University of Edinburgh (United Kingdom)
Azim Surani, Professor at the University of Cambridge (United Kingdom)
Biola Javierre, Principal Investigator at the Josep Carreras Leukaemia Research Institute (Spain)
Daniel Jarosz, Associate Professor at Stanford University (USA)
Daniel Martin Messerschmidt, Associate Professor at University of Copenhagen (Denmark)
Hiten Madhani, Professor at the University of California San Francisco (USA)
Jessica Downs, Professor at the Institute of Cancer Research (United Kingdom)
Julie Ahringer, Professor at the University of Cambridge (United Kingdom)
Oliver Rando, Professor at the University of Massachusetts Medical School (USA)
Pablo Navarro Gil, Principal Investigator at the Institut Pasteur (France)
Sylvia Erhardt, Professor at the Karlsruhe Institute of Technology (Germany)
Ueli Grossniklaus, Professor at the University of Zurich (Switzerland)
Wolf Reik, Director of the Altos Cambridge Institute of Science (United Kingdom)
This multidisciplinary workshop aims to tackle the various dimensions of epigenetic regulation by providing a valuable platform for epigenetic researchers working with different model organisms to exchange knowledge, share recent findings and foster collaborative efforts in order to accelerate advancements in the field. Attendance is restricted to 35 people to complete a group of 50 including the invited speakers. A major objective of this workshop is to promote interaction between junior scientists (young PIs, postdoctoral fellows, graduate students) and well-recognized senior investigators in the field. Both the venue and the small number of attendants will provide a unique forum for fruitful discussions to exchange knowledge, share recent unpublished findings and foster collaborative efforts. "See application guidelines".
FORMATE OF THE WORKSHOP:
The workshop will bring together 15 speakers and a maximum of 35 participants. The scientific programme will start on Tuesday 15th of October in the morning and will end on Thursday 17th of October in the morning. Ample time for informal discussion will be reserved. Participants are encouraged to present a poster. A considerable number of submitted abstracts will be selected for short talks.
The workshop will be held in Baeza, at the “Antonio Machado Headquarters”, a XVII century building turned into a Conference Centre of the International University of Andalusia (UNIA). A complex made up of two historic buildings: the Jabalquinto Palace (XV/XVI centuries) and the old Seminary (XVII century) located in the heart of the historic complex, among the old University, church of Santa Cruz, the cathedral and the Upper Town Halls.
This site includes a recently restored residence, where speakers and participants will be accommodated. This same space is where the meetings will be held, which facilitates social interaction and informal discussions.
Baeza is a world historic heritage town, renowned for its Renaissance and Gothic buildings.
ACCOMMODATION:
We recommend all participants to stay in the University Residence, which is located in the same space where the Meetings will take place, to facilitate social interaction and informal discussions.
The accommodation in the University Residence is in shared double rooms, as there are not single rooms: €20/day. To make the reservation and the corresponding payment you must be previously registered for the workshop and then contact:
WORKSHOP REGISTRATION:
A) Applicants must complete an application form and submit it, along with:
- A brief C.V.
- A summary of the current research work of the candidate.
In case of presenting a poster, a summary of the poster of no more than one page, with the title, authorship, research center/institution/university, address and a summary of the communication.
See section "presentation of panels and posters”.
SEE LINK TO:
Application form (odt)
Application form (doc)*:
En cumplimiento del Reglamento General de Protección de Datos (Reglamento (UE) 2016/679), se le informa que los datos personales que se puedan recopilar se incorporarán y procesarán en algunos de los archivos de la Universidad Internacional de Andalucía (UNIA); los datos pueden divulgarse según lo previsto por la ley.
La autoridad responsable de los datos es: UNIA: Secretaría General (Secretario General). C / Américo Vespucio nº 2, Isla de la Cartuja. 41092 - SEVILLA, ESPAÑA.
Puede ejercer sus derechos de acceso, rectificación, eliminación y oposición contactando por escrito con la dirección mencionada anteriormente, a la atención del Delegado de Protección de Datos, o enviando un correo electrónico a
B) Send the completed Application Form (doc/odt) and the attached documents as separate text files and in a single email message, to
Selected applicants (with or without poster) will be notified directly. From that moment on, they must pay the corresponding registration fees*.
WORKSHOP FEES 2024:
Registration: 400,00 € (breakfast, lunch, coffe-breaks and dinner included)
Payment method: bank transfer to ‘La Caixa’
IBAN (international bank account number): ES78 21009166752200074348
SWIFT (BIC): CAIXESBBXXX
Registration fees deadline 27 September 2024
Selected applicants must indicate their full name and code number (it will appear in the webpage) in the bank transfer. After completing your payment by bank transfer, a proof of payment must be sent to:
The bank charges generated by the bank transfer will be paid by the applicants/attendees.
WORKSHOP panels/posters guidelines:
The scheduled dates for the presentation of panels/posters are:
A. Deadline to present the complete panels in digital format 26 AUGUST 2024.
Presentation of the proposal: through the registration form in the Worhshop.
Shipping address for panels/posters:
o For the oral presentation of posters it is essential to have formalized registration and payment of the Workshop.
o The co-director of the Workshop will indicate and assign the session in which to present the work.
o The organization will certify the effective presentation of each panel/poster during the Workshop.
o Each author individually or collectively may present a maximum of 2 panels.
o Researchers may display their panel in the campus facilities. To do this, they must bring their work printed in DIN A0 vertical format (84.1 x 118.9 cm) and arrange it in the provided fastening systems.
Panel/poster contents:
• Title: Arial bold 14 points.
• Subtitle (if applicable).
• Authorship (individual or collective).
• Keywords: maximum 4.
• Presentation / Summary of content: 120 words.
• Methodology: 100 words.
• Description and contents: through text and graphics.
• Conclusions: maximum 100 words
• Sources and essential bibliography.
• Format: to transfer digitally DIN A4; PDF. Type: Arial. Body: minimum 9 and maximum 12 points.
Matrícula y becas
Situación actual:
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pendiente inicio
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