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Formación continua/ Ciencias/ B/164

Workshop: THE ROLE OF MICROGLIA IN NEURODEVELOPMENTAL AND NEURODEGENERATIVE DISORDERS/B164

D. José Luis Venero. Instituto de Biomedicina de Sevilla (IBiS). Departamento de Bioquímica y Biología Molecular, Facultad de Farmacia. Sevilla.

D. Bertrand Joseph. Karolinska Institutet. Institute of Environmental Medicine The Chinese University of Hong Kong. Center for Neuromusculoskeletal Restorative Medicine.

  • pendiente inicio
  • Fecha de inicio
    Desde: 23 Septiembre 2025
  • Hasta: 25 Septiembre 2025
  • Presencial
  • Investigadora
  • Preferentemente inglés
  • 20 horas
  • 400 euros
  • 35

Introduction

Microglia, the resident immune cells of the central nervous system, play a pivotal role in both neurodevelopment and neurodegeneration. During brain development, microglia contribute to synaptic pruning, neuronal maturation, and circuit refinement, ensuring proper connectivity and function. Their dynamic interactions with neurons and glial cells are essential for shaping the neural environment and maintaining homeostasis. However, microglial dysfunction has been implicated in various neurodevelopmental disorders, including autism spectrum disorder and schizophrenia.

In the aging brain and under pathological conditions, microglia shift toward a reactive state, contributing to neuroinflammation and neurodegeneration. Chronic activation of microglia has been associated with Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative disorders, where their inflammatory responses may exacerbate neuronal damage. Emerging research highlights the heterogeneity of microglial states, with specific phenotypes linked to either protective or detrimental outcomes. Understanding the molecular mechanisms underlying microglial function and dysfunction is essential for developing targeted therapeutic strategies.

This workshop will bring together leading researchers to discuss the latest advances in microglial biology, their contributions to neural development and degeneration, and emerging therapeutic approaches. Through interdisciplinary discussions, we aim to foster new insights into microglial function and their potential as targets for intervention in neurological diseases.

Expected Impact

This workshop aims to provide a platform for discussing groundbreaking research on microglia and their role in the nervous system. Key objectives include:

• Showcasing cutting-edge research on microglial biology and its implications in neurodevelopmental and neurodegenerative disorders.
• Encouraging collaborations between senior and early-career researchers.
• Facilitating knowledge exchange through interactive discussions and poster presentations.
• Highlighting novel therapeutic approaches targeting microglial dysfunction.

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